DENND1C Protein (Myc-DYKDDDDK Tag)
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- Target Alle DENND1C Proteine anzeigen
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses DENND1C Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human DENND1C protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DENND1C Protein
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DENN/MADD Domain Containing 1C (DENND1C) (AA 1-801) protein (Strep Tag)
Crystallography grade DENND1C Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
DENN/MADD Domain Containing 1C (DENND1C) (AA 1-786) protein (Strep Tag)Crystallography grade DENND1C Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Abstract
- DENND1C Produkte
- Synonyme
- FAM31C Protein, 4432409M07Rik Protein, DENN/MADD domain containing 1C L homeolog Protein, DENN/MADD domain containing 1C Protein, DENN domain containing 1C Protein, dennd1c.L Protein, DENND1C Protein, Dennd1c Protein
- Hintergrund
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2 see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010].
- Molekulargewicht
- 86.9 kDa
- NCBI Accession
- NP_079174
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