DDX1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719273

Produktdetails

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DDX1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human DDX1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Lin, Sivakumaran, Jones, Li, Harper, Wei, Jin, Rustanti, Meunier, Spann, Harrich: "A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1." in: Retrovirology, Vol. 11, pp. 121, (2015) (PubMed).

Antigendetails

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Andere Bezeichnung: Ddx1 (DDX1 Produkte)

Synonyme: CG9054 Protein, DDX1 Protein, Dbp79E Protein, DmDDX1 Protein, DmRH12 Protein, Dmel\\CG9054 Protein, anon-79E Protein, DBP-RB Protein, UKVH5d Protein, si:ch211-214k9.2 Protein, si:dkey-161f12.1 Protein, AA409185 Protein, Dead-box-1 Protein, DEAD-box helicase 1 Protein, DEAD/H-box helicase 1 L homeolog Protein, DEAD (Asp-Glu-Ala-Asp) box helicase 1 Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 Protein, Ddx1 Protein, DDX1 Protein, ddx1.L Protein, ddx1 Protein

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Molekulargewicht: 82.3 kDa

NCBI Accession: NP_004930

Pathways: Ribonucleoprotein Complex Subunit Organization