MRNIP/C5ORF45 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2718602

Produktdetails

Target: MRNIP/C5ORF45 (C5ORF45) (Chromosome 5 Open Reading Frame 45 (C5ORF45))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MRNIP/C5ORF45 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human C5orf45 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MRNIP/C5ORF45 (C5ORF45) (Chromosome 5 Open Reading Frame 45 (C5ORF45))

Abstract: C5ORF45 Produkte

Synonyme: 2900016G09Rik Protein, AI851514 Protein, AW475975 Protein, MRN complex interacting protein Protein, zgc:123335 Protein, MRNIP Protein, Mrnip Protein, zgc:123335 Protein

Hintergrund: Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex (PubMed:27568553). Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair (PubMed:27568553). [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 37.6 kDa

NCBI Accession: NP_057259