BMX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715316

Produktdetails

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BMX Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human BMX (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Biological Activity Comment: BMX activity verified in a biochemical assay:,BMX activity verified in a biochemical assay:

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: > 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Andere Bezeichnung: Bmx (BMX Produkte)

Synonyme: BMX Protein, ETK Protein, PSCTK2 Protein, PSCTK3 Protein, Etk Protein, Etk/Bmx Protein, Tyro8 Protein, RGD1565643 Protein, BMX non-receptor tyrosine kinase Protein, BMX Protein, bmx Protein, Bmx Protein

Hintergrund: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 77.8 kDa

NCBI Accession: NP_001712