AUH Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715079

Produktdetails

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses AUH Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human AUH protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Andere Bezeichnung: Auh (AUH Produkte)

Synonyme: C77140 Protein, W91705 Protein, wu:fb81b10 Protein, zgc:101057 Protein, AU RNA binding methylglutaconyl-CoA hydratase Protein, AU RNA binding protein/enoyl-coenzyme A hydratase Protein, AU RNA binding protein/enoyl-CoA hydratase Protein, AU RNA binding protein/enoyl-CoA hydratase S homeolog Protein, AUH Protein, Auh Protein, auh Protein, auh.S Protein

Hintergrund: This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 29.1 kDa

NCBI Accession: NP_001689