ASPSCR1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715005

Produktdetails

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ASPSCR1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ASPSCR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Andere Bezeichnung: Aspscr1 (ASPSCR1 Produkte)

Synonyme: tug Protein, aspl Protein, asps Protein, rcc17 Protein, ubxd9 Protein, aspcr1 Protein, ASPCR1 Protein, ASPL Protein, ASPS Protein, RCC17 Protein, TUG Protein, UBXD9 Protein, UBXN9 Protein, 1190006K01Rik Protein, ASPC Protein, ASPSCR1, UBX domain containing tether for SLC2A4 Protein, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog Protein, alveolar soft part sarcoma chromosome region, candidate 1 Protein, alveolar soft part sarcoma chromosome region, candidate 1 (human) Protein, ASPSCR1 Protein, aspscr1.S Protein, Aspscr1 Protein, aspscr1 Protein, Bm1_55980 Protein

Hintergrund: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X17)(p11q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Molekulargewicht: 60 kDa

NCBI Accession: NP_076988