ANAPC2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714781

Produktdetails

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ANAPC2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human APC2 / ANAPC2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Andere Bezeichnung: Apc2,anapc2 (ANAPC2 Produkte)

Synonyme: anapc2 Protein, ANAPC2 Protein, DDBDRAFT_0203816 Protein, DDBDRAFT_0234264 Protein, DDB_0203816 Protein, DDB_0234264 Protein, si:ch73-203i15.5 Protein, APC2 Protein, RP11-350O14.5 Protein, 9230107K09Rik Protein, AL024279 Protein, Apc2 Protein, Emi4 Protein, Imi4 Protein, mKIAA1406 Protein, F28I8.30 Protein, F28I8_30 Protein, anaphase-promoting complex/cyclosome 2 Protein, anaphase promoting complex subunit 2 Protein, anaphase promoting complex subunit 2 L homeolog Protein, anaphase-promoting complex/cyclosome 2 Protein, Anaphase-promoting complex subunit 2 Protein, ANAPC2 Protein, anapc2.L Protein, anapc2 Protein, Anapc2 Protein, APC2 Protein, apc-2 Protein

Hintergrund: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Molekulargewicht: 93.6 kDa

NCBI Accession: NP_037498

Pathways: Regulation of Cell Size