AGR2 Protein (His tag)
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- Target Alle AGR2 Proteine anzeigen
- AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses AGR2 Protein ist gelabelt mit His tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human AGR2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin-Niveau
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product AGR2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the N-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
- Andere Bezeichnung
- Agr2 (AGR2 Produkte)
- Synonyme
- AG2 Protein, GOB-4 Protein, HAG-2 Protein, PDIA17 Protein, XAG-2 Protein, Agr2h Protein, Gob-4 Protein, mAG-2 Protein, wu:fj29g05 Protein, zgc:112187 Protein, agr2 Protein, hag3 Protein, hag-3 Protein, bcmp11 Protein, MGC89004 Protein, XAgr2 Protein, agr2-A Protein, anterior gradient 2, protein disulphide isomerase family member Protein, anterior gradient 2 Protein, anterior gradient 3, protein disulphide isomerase family member Protein, anterior gradient 2, protein disulphide isomerase family member S homeolog Protein, AGR2 Protein, Agr2 Protein, agr2 Protein, agr3 Protein, agr2.S Protein
- Hintergrund
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.
- Molekulargewicht
- 18.9 kDa
- NCBI Accession
- NP_006399
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