ASCC1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714362

Produktdetails

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ASCC1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Activating signal cointegrator 1 complex subunit 1 (ASCC1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Abstract: ASCC1 Produkte

Synonyme: ASC1p50 Protein, p50 Protein, Asc-1 Protein, CGI-18 Protein, 1810015P09Rik Protein, AI550520 Protein, activating signal cointegrator 1 complex subunit 1 Protein, ascc1 Protein, ASCC1 Protein, Ascc1 Protein

Hintergrund: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 41 kDa

NCBI Accession: NP_057031