HSD17B3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714229

Produktdetails

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HSD17B3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human 17-beta-HSD3 / HSD17B3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Andere Bezeichnung: 17-beta-Hsd3,hsd17b3 (HSD17B3 Produkte)

Synonyme: EDH17B3 Protein, SDR12C2 Protein, hydroxysteroid (17-beta) dehydrogenase 3 Protein, hydroxysteroid 17-beta dehydrogenase 3 Protein, Hsd17b3 Protein, HSD17B3 Protein

Hintergrund: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Molekulargewicht: 34.3 kDa

NCBI Accession: NP_000188

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis