CFHR1 Protein (His tag)

Produktnummer ABIN2713938

Produktdetails

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CFHR1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human CFHR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Andere Bezeichnung: Cfhr1 (CFHR1 Produkte)

Synonyme: AI194696 Protein, CFHRB Protein, Cfhl1 Protein, CFHL Protein, CFHL1 Protein, CFHL1P Protein, CFHR1P Protein, FHR1 Protein, H36-1 Protein, H36-2 Protein, HFL1 Protein, HFL2 Protein, complement factor H-related 1 Protein, complement factor H-related protein 1 Protein, complement factor H related 1 Protein, Cfhr1 Protein, LOC735590 Protein, LOC746429 Protein, CFHR1 Protein

Hintergrund: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Molekulargewicht: 36.78kD

NCBI Accession: NP_002104