CCBL1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target Alle CCBL1 Proteine anzeigen
- CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- Transcript Variant 1
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CCBL1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- Spezifität
- Optimal preservation of protein structure, post-translational modifications and functions.
- Produktmerkmale
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- Recombinant human CCBL1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Biological Activity Comment
- The specific activity of KATI was determined by measuring the product Kynurenic acid formation from a conversion of Kynurenine. The reaction was carried out at 37? for 15min in the buffer containing 100 mM PBS, pH7.4, 2 mM a-oxoglutarate, 40μM PLP (pyridoxal 5'-phosphate), and 0.5 mM kynurenine as the substrate.
- Top Product
- Discover our top product CCBL1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- > 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))
- Andere Bezeichnung
- Ccbl1 (CCBL1 Produkte)
- Synonyme
- 2010009K05Rik Protein, AI182306 Protein, Gtk Protein, Kat1 Protein, KatI Protein, GTK Protein, KAT1 Protein, KATI Protein, kynurenine aminotransferase 1 Protein, Kyat1 Protein, KYAT1 Protein
- Hintergrund
- This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
- Molekulargewicht
- 47.7 kDa
- NCBI Accession
- NP_004050
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