CNOT7 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712912

Produktdetails

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CNOT7 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CNOT7 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: Cnot7 (CNOT7 Produkte)

Synonyme: CNOT7 Protein, CAF1 Protein, fd59c07 Protein, fj07d05 Protein, wu:fd59c07 Protein, wu:fj07d05 Protein, zgc:153168 Protein, caf1 Protein, Caf1a Protein, hCAF-1 Protein, AU022737 Protein, CAF-1 Protein, Caf1 Protein, Pop2 Protein, CCR4-NOT transcription complex subunit 7 Protein, ccr4-not transcription complex, subunit 7 Protein, CCR4-NOT transcription complex, subunit 7 Protein, ccr4-not transcription complex, subunit 7, putative Protein, CCR4-NOT transcription complex subunit 7 S homeolog Protein, CNOT7 Protein, CNL04550 Protein, GL50803_10606 Protein, GL50803_8209 Protein, CGB_D2510C Protein, cnot7 Protein, cnot7.S Protein, Cnot7 Protein

Hintergrund: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Molekulargewicht: 32.6 kDa

NCBI Accession: NP_037486

Pathways: Ribonucleoprotein Complex Subunit Organization