GARP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712908

Produktdetails

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GARP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CNGB1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Andere Bezeichnung: Cngb1 (CNGB1 Produkte)

Synonyme: CNCG2 Protein, CNCG3L Protein, CNCG4 Protein, CNG4 Protein, CNGB1B Protein, GAR1 Protein, GARP Protein, RCNC2 Protein, RCNCb Protein, RCNCbeta Protein, RP45 Protein, Gm1959 Protein, Cngb1b Protein, CNGB1 Protein, si:ch211-160j6.1 Protein, cyclic nucleotide gated channel beta 1 Protein, cyclic nucleotide gated channel beta 1a Protein, CNGB1 Protein, Cngb1 Protein, cngb1a Protein

Hintergrund: In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 32.4 kDa

NCBI Accession: NP_001129111

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction