CLN6 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712884

Produktdetails

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CLN6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CLN6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Andere Bezeichnung: Cln6 (CLN6 Produkte)

Synonyme: 1810065L06Rik Protein, AW743417 Protein, D9Bwg1455e Protein, nclf Protein, CLN4A Protein, HsT18960 Protein, cln6 Protein, zgc:103565 Protein, ceroid-lipofuscinosis, neuronal 6 Protein, CLN6, transmembrane ER protein Protein, CLN6, transmembrane ER protein S homeolog Protein, ceroid-lipofuscinosis, neuronal 6, late infantile, variant Protein, CLN6, transmembrane ER protein a Protein, Cln6 Protein, CLN6 Protein, cln6.S Protein, cln6a Protein

Hintergrund: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Molekulargewicht: 35.7 kDa

NCBI Accession: NP_060352

Pathways: Glycosaminoglycan Metabolic Process