Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712510

Produktdetails

Target: Coronin 7 (CORO7)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Coronin 7 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Coronin-7 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Coronin 7 (CORO7)

Abstract: CORO7 Produkte

Synonyme: coronin-7 Protein, zgc:112352 Protein, MGC99303 Protein, Coronin-7 Protein, DKFZp459E084 Protein, 0610011B16Rik Protein, CRN7 Protein, POD1 Protein, AW048373 Protein, AW556392 Protein, Crn7 Protein, coronin 7 Protein, coronin 7 S homeolog Protein, coronin-7 Protein, CORO7 Protein, coro7 Protein, coro7.S Protein, LOC100477739 Protein, Coro7 Protein

Hintergrund: This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants some of which form read-through transcripts with a neighboring gene.

Molekulargewicht: 100.4 kDa

NCBI Accession: NP_078811