Tyrosine Hydroxylase Protein (TH) (Transcript Variant 2, Tyr3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712391

Produktdetails

Target: Tyrosine Hydroxylase (TH)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2, Tyr3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Tyrosine Hydroxylase Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Tyrosine 3-monooxygenase (TH) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Tyrosine Hydroxylase (TH)

Andere Bezeichnung: Tyrosine 3-Monooxygenase (Th) (TH Produkte)

Synonyme: DYT14 Protein, DYT5b Protein, TYH Protein, The Protein, CG10118 Protein, DH65B Protein, DTH Protein, Dmel\\CG10118 Protein, Pale Protein, Ple Protein, TH Protein, Th Protein, VII Protein, dTH1 Protein, dTH65B Protein, pale/ple Protein, th Protein, dyt14 Protein, dyt5b Protein, tyh Protein, tyrosine hydroxylase Protein, pale Protein, tyrosine 3-monooxygenase Protein, tyrosine hydroxylase S homeolog Protein, TH Protein, Th Protein, ple Protein, th Protein, th.S Protein, LOC100008895 Protein

Hintergrund: The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molekulargewicht: 55.4 kDa

NCBI Accession: NP_000351

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour