SETMAR Protein (DYKDDDDK Tag)
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- Target Alle SETMAR Proteine anzeigen
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Baculovirus
- Aufreinigungstag / Konjugat
- Dieses SETMAR Protein ist gelabelt mit DYKDDDDK Tag.
- Applikation
- Enzyme Activity Assay (EAA), Screening Assay (ScA)
- Produktmerkmale
- Recombinant SETMAR (accession number NP_006506.3) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 79 kDa.
- Top Product
- Discover our top product SETMAR Protein
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SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-352) protein (GST tag)
SETMAR Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-684) protein (Strep Tag)Crystallography grade SETMAR Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-309) protein (Strep Tag)Crystallography grade SETMAR Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-118), (full length) protein (His tag)SETMAR Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
SET Domain and Mariner Transposase Fusion Gene (SETMAR) protein (Myc-DYKDDDDK Tag)SETMAR Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
- Recombinant SETMAR is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Handhabung
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Target
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Andere Bezeichnung
- SETMAR (SETMAR Produkte)
- Synonyme
- HsMar1 Protein, METNASE Protein, Mar1 Protein, 5830404F24Rik Protein, Etet2 Protein, SETMAR Protein, zgc:172212 Protein, SET domain and mariner transposase fusion gene Protein, SET domain without mariner transposase fusion Protein, histone-lysine N-methyltransferase SETMAR Protein, SETMAR Protein, Setmar Protein, LOC470738 Protein, setmar Protein, LOC703880 Protein, LOC100447656 Protein, LOC100586616 Protein
- Hintergrund
- SETMAR (SET Domain and mariner transposase fusion gene) is a ubiquitously expressed nuclear fusion protein that contains an N-terminal SET domain with histone methyltransferase activity and a C-terminal mariner (MAR) transposase domain that recognizes and binds DNA. The gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. SETMAR binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The mariner transposase domain recognizes and binds the 19-mer core of the 5'-TIR (terminal inverted repeats) of the Hsmar1 element. The SET domain specifically methylates lysines 4 and 36 of histone H3 which are epigenetic marks associated with transcriptional activation. SETMAR demonstrates in vivo end joining activity and may mediate genomic integration of foreign DNA.
- Molekulargewicht
- 79 kDa
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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