BRD9 Protein (AA 130-259) (His tag,DYKDDDDK Tag)

Produktnummer ABIN2669647

Produktdetails

Target: BRD9 (Bromodomain Containing 9 (BRD9))

Protein-Typ: Recombinant

Proteineigenschaft: AA 130-259

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BRD9 Protein ist gelabelt mit His tag,DYKDDDDK Tag.

Applikation: Binding Studies (Bind), Screening Assay (ScA)

Produktmerkmale: The peptide corresponding to amino acids 130 - 259 that contains the bromodomain sequences of BRD9 (accession number NM_023924.4) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.9 kDa.

Anwendungsinformationen

Applikationshinweise: Recombinant BRD9 (130-259) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Antigendetails

Target: BRD9 (Bromodomain Containing 9 (BRD9))

Andere Bezeichnung: BRD9 (BRD9 Produkte)

Synonyme: LAVS3040 Protein, PRO9856 Protein, AL022779 Protein, zgc:55797 Protein, BRD9 Protein, bromodomain containing 9 Protein, bromodomain containing 9 L homeolog Protein, BRD9 Protein, Brd9 Protein, brd9 Protein, brd9.L Protein

Hintergrund: Bromodomain-containing protein 9 (BRD9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.

Molekulargewicht: 20.9 kDa