Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IL-33 Protein (AA 1-270) (His tag)

IL33 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ~95 % WB, ELISA, MS, Neut
Produktnummer ABIN2468679
  • Target Alle IL-33 (IL33) Proteine anzeigen
    IL-33 (IL33) (Interleukin 33 (IL33))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-270
    Spezies
    • 22
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 29
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses IL-33 Protein ist gelabelt mit His tag.
    Applikation
    Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
    Reinheit
    ~95 %
    Top Product
    Discover our top product IL33 Protein
  • Applikationshinweise
    This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    100 mM sodium phosphate, 500 mM NaCl, 25 mM imidazole, 10 % gycerol
    Handhabung
    Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store in working aliquots at -70 °C.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Andere Bezeichnung
    IL-33 (IL33 Produkte)
    Synonyme
    IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
    Hintergrund
    Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1???, IL-1Ra and IL-18 (1,2). Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling (1,3) and IL-1R accessory protein (IL-1RAcP) (4). Receptor binding of IL-33 activates NF-?B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine (2). Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties (5).
    Molekulargewicht
    30 kDa (Calculated)
    Gen-ID
    90865
    NCBI Accession
    NP_254274
    OMIM
    15559209
    UniProt
    O95760
    Pathways
    Production of Molecular Mediator of Immune Response
Sie sind hier:
Kundenservice