GPRASP1 Protein
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- Target Alle GPRASP1 Proteine anzeigen
- GPRASP1 (G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- CHO Cells
- Sequenz
- LPPIRYSHAG ICPNDMNPNL WVDAQSTCRR ECETDQECET YEKCCPNVCG TKSCVAARYM DVKGKKGPVG MPKEATCDHF MCLQQGSECD IWDGQPVCKC KDRCEKEPSF TCASDGLTYY NRCYMDAEAC SKGITLAVVT CRYHFTWPNT SPPPPETTMH PTTASPETPE LDMAAPALLN NPVHQSVTMG ETVSFLCDVV GRPRPEITWE KQLEDRENVV MRPNHVRGNV VVTNIAQLVI YNAQLQDAGI YTCTARNVAG VLRADFPLSV VRGHQAAATS ESSPNGTAFP AAECLKPPDS EDCGEEQTRW HFDAQANNCL TFTFGHCHRN LNHFETYEAC MLACMSGPLA ACSLPALQGP CKAYAPRWAY NSQTGQCQSF VYGGCEGNGN NFESREACEE SCPFPRGNQR CRACKPRQKL VTSFCRSDFV ILGRVSELTE EPDSGRALVT VDEVLKDEKM GLKFLGQEPL EVTLLHVDWA CPCPNVTVSE MPLIIMGEVD GGMAMLRPDS FVGASSARRV RKLREVMHKK TCDVLKEFLG LH
- Produktmerkmale
- Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 μg/mL in the presence of 5 ng/mL of human Myostatin (GDF-8).
- Reinheit
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Top Product
- Discover our top product GPRASP1 Protein
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G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) (AA 1-1395) protein (Strep Tag)
Crystallography grade GPRASP1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) (AA 1-1347) protein (Strep Tag)Crystallography grade GPRASP1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Handhabung
- As with any protein, exposing GASP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GASP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Haltbarkeit
- 24 months
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- Target
- GPRASP1 (G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1))
- Andere Bezeichnung
- GASP-1 (GPRASP1 Produkte)
- Synonyme
- pips Protein, 2210415K24Rik Protein, 3110031O14Rik Protein, C87852 Protein, GASP Protein, GASP1 Protein, GASP-1 Protein, G protein-coupled receptor associated sorting protein 1 Protein, Gprasp1 Protein, GPRASP1 Protein
- Hintergrund
- Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions.
- Gen-ID
- 9737
- NCBI Accession
- NP_001092880
- OMIM
- 150378489
- UniProt
- Q5JY77
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