This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.3 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
HSA
Spezies: Human
Wirt: non-mammalian expression system
Recombinant
> 96 %
CC
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
PBS, pH 7.4
Handhabung
Please avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Siaw, Raghunath, Dyer: "Peripheral Protein Unfolding Drives Membrane Bending." in: Langmuir : the ACS journal of surfaces and colloids, Vol. 34, Issue 28, pp. 8400-8407, (2019) (PubMed).
Happonen, Hauri, Svensson Birkedal, Karlsson, de Neergaard, Khakzad, Nordenfelt, Wikström, Wisniewska, Björck, Malmström, Malmström: "A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies." in: Nature communications, Vol. 10, Issue 1, pp. 2727, (2019) (PubMed).
PRO0883 Protein, PRO0903 Protein, PRO1341 Protein, albumin Protein, ALB Protein
Hintergrund
Serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80 % of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.