WFDC2 Protein (AA 31-124) (His tag)

Produktnummer ABIN2181198

Produktdetails

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-124

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses WFDC2 Protein ist gelabelt mit His tag.

Sequenz: AA 31-124

Produktmerkmale: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.9 kDa. The protein migrates as 19 kDa and 22-26 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Referenzen

Yang, Lu, Guo, Fellman, Ning, Lu, Menon, Kobayashi, Hanash, Celestino, Skates, Bast: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).

Antigendetails

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Andere Bezeichnung: HE4 (WFDC2 Produkte)

Synonyme: WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein

Hintergrund: Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.

Molekulargewicht: 10.9 kDa