SLC3A2 Protein (AA 206-630) (His tag)

Produktnummer ABIN2180859

Produktdetails

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 206-630

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SLC3A2 Protein ist gelabelt mit His tag.

Sequenz: AA 206-630

Produktmerkmale: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 47.7 kDa. The protein migrates as 50-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Andere Bezeichnung: CD98 (SLC3A2 Produkte)

Synonyme: 4F2 Protein, 4F2HC Protein, 4T2HC Protein, CD98 Protein, CD98HC Protein, MDU1 Protein, NACAE Protein, Mdu1 Protein, MGC53951 Protein, slc3a2 Protein, MGC53965 Protein, SLC3A2 Protein, AI314110 Protein, Cd98 Protein, Ly-10 Protein, Ly-m10 Protein, Ly10 Protein, Mgp-2hc Protein, fc65h12 Protein, wu:fc65h12 Protein, id:ibd1327 Protein, sb:cb519 Protein, wu:fe14a07 Protein, wu:fq18d12 Protein, zgc:55813 Protein, solute carrier family 3 member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog Protein, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2a Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2b Protein, SLC3A2 Protein, Slc3a2 Protein, slc3a2.L Protein, slc3a2.S Protein, slc3a2a Protein, slc3a2b Protein

Hintergrund: CD antigen CD98 is also known as 4F2 cell-surface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain amino-acid transporters and also involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals.

Molekulargewicht: 47.7 kDa