CCL23 Protein (AA 32-494, AA 495-728)

Produktnummer ABIN2018262

Produktdetails

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 32-494, AA 495-728

Spezies: Human

Quelle: CHO Cells

Produktmerkmale: The EC50 value of human MPIF-1/CCL23 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 2 μg/mL.
Alpha chain: AA 32-494, beta chain: AA 495-728

Reinheit: > 98 % as analyzed by SDS-PAGE.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant humanMPIF-1/CCL23 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human MPIF-1/CCL23 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Andere Bezeichnung: MPIF-1/CCL23 (CCL23 Produkte)

Synonyme: CK-BETA-8 Protein, CKb8 Protein, Ckb-8 Protein, Ckb-8-1 Protein, MIP-3 Protein, MIP3 Protein, MPIF-1 Protein, SCYA23 Protein, hmrp-2a Protein, C-C motif chemokine 23 Protein, C-C motif chemokine ligand 23 Protein, chemokine (C-C motif) ligand 23 Protein, LOC508666 Protein, CCL23 Protein

Hintergrund: Myeloid progenitor inhibitory factor 1 (MPIF-1), also known as Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.MPIF-1is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. It is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. MPIF-1 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. MPIF-1 is a ligand for the chemokine receptor CCR1.Recombinant human MPIF-1/CCL23 produced in CHO cells is a single polypeptide chain containing 99 amino acids. A fully biologically active molecule, rhMPIF-1/CCL23 has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE.
Synonyms: MPIF-1/CCL23, Human

Molekulargewicht: 12 kDa, observed by reducing SDS-PAGE.