Crystallography grade
GTSE1
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS, Crys
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-80 °C
Informationen zur Lagerung
Best use within three months from the date of receipt of this protein.
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Hintergrund
Synonyms: B99 Gene Description: G-2 and S-phase expressed 1 Gene Name: GTSE1 Gene Summary: The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. GenBank: AK315550.1, BAG37928.1