NR4A3 Protein (AA 1-626) (GST tag)

Produktnummer ABIN1989820

Produktdetails

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-626

Spezies: Human

Quelle: Wheat germ

Aufreinigungstag / Konjugat: Dieses NR4A3 Protein ist gelabelt mit GST tag.

Applikation: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Verwendungszweck: NR4A3 (Human) Recombinant Protein (P01)

Sequenz: MPCVQAQYSP SPPGSSYAAQ TYSSEYTTEI MNPDYTKLTM DLGSTEITAT ATTSLPSIST FVEGYSSNYE LKPSCVYQMQ RPLIKVEEGR APSYHHHHHH HHHHHHHHQQ QHQQPSIPPA SSPEDEVLPS TSMYFKQSPP STPTTPAFPP QAGALWDEAL PSAPGCIAPG PLLDPPMKAV PTVAGARFPL FHFKPSPPHP PAPSPAGGHH LGYDPTAAAA LSLPLGAAAA AGSQAAALES HPYGLPLAKR AAPLAFPPLG LTPSPTASSL LGESPSLPSP PSRSSSSGEG TCAVCGDNAA CQHYGVRTCE GCKGFFKRTV QKNAKYVCLA NKNCPVDKRR RNRCQYCRFQ KCLSVGMVKE VVRTDSLKGR RGRLPSKPKS PLQQEPSQPS PPSPPICMMN ALVRALTDST PRDLDYSRYC PTDQAAAGTD AEHVQQFYNL LTASIDVSRS WAEKIPGFTD LPKEDQTLLI ESAFLELFVL RLSIRSNTAE DKFVFCNGLV LHRLQCLRGF GEWLDSIKDF SLNLQSLNLD IQALACLSAL SMITERHGLK EPKRVEELCN KITSSLKDHQ SKGQALEPTE SKVLGALVEL RKICTLGLQR IFYLKLEDLV SPPSIIDKLF LDTLPF

Produktmerkmale: Human NR4A3 full-length ORF (NP_008912.2, 1 a.a. - 626 a.a.) recombinant protein with GST tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Antigendetails

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Andere Bezeichnung: NR4A3 (NR4A3 Produkte)

Synonyme: CHN Protein, CSMF Protein, MINOR Protein, NOR1 Protein, TEC Protein, AI573420 Protein, NOR-1 Protein, Nor1 Protein, NOR-2 Protein, NR4A3 Protein, Nr4a3 Protein, nuclear receptor subfamily 4 group A member 3 Protein, nuclear receptor subfamily 4, group A, member 3 Protein, NR4A3 Protein, Nr4a3 Protein, nr4a3 Protein

Hintergrund: Synonyms: CHN,CSMF,MINOR,NOR1,TEC
Gene Description: nuclear receptor subfamily 4, group A, member 3
Gene Name: NR4A3
Gene Summary: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene.

Molekulargewicht: 94.6 kDa (theoreatical)

Gen-ID: 8013

NCBI Accession: NM_006981

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway