Recombinant Human Neural proliferation differentiation and control protein 1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 35-181) of Human NPDC1 fused with a 6His tag at the C-terminus.
Reinheit
> 95 % as determined by reducing SDS-PAGE.
Sterilität
0.2 μm filtered
Endotoxin-Niveau
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Crystallography grade
NPDC1
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
NPDC1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
Handhabung
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung
4 °C/-20 °C/-80 °C
Informationen zur Lagerung
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Target
NPDC1
(Neural Proliferation, Differentiation and Control, 1 (NPDC1))
Andere Bezeichnung
Neural Proliferation Differentiation and Control Protein 1 (NPDC1 Produkte)
Synonyme
AI314472 Protein, NPDC-1 Protein, CAB Protein, CAB- Protein, CAB-1 Protein, CAB1 Protein, neural proliferation, differentiation and control, 1, gene 1 L homeolog Protein, neural proliferation, differentiation and control 1 Protein, neural proliferation, differentiation and control, 1 Protein, npdc1.1.L Protein, Npdc1 Protein, NPDC1 Protein
Hintergrund
Neural proliferation differentiation and control protein 1(NPDC1) is a protein that in humans is encoded by the NPDC1 gene. It is a single-pass membrane protein and belongs to the NPDC1/cab-1 family. The protein strongly expressed in adult brain and especially in hippocampus, frontal lobe and temporal lobe. The protein suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation and it might be involved in transcriptional regulation.