FAM19A4 Protein (AA 35-140) (His tag)

Produktnummer ABIN1945371

Produktdetails

Target: FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 35-140

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FAM19A4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Protein FAM19A4/FAM19A4 (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MSSQHLRGHA GHHQIKQGTC EVVAVHRCCN KNRIEERSQT VKCSCFPGQV AGTTRAQPSC VEASIVIQKW WCHMNPCLEG EDCKVLPDYS GWSCSSGNKV KTTKVTR

Produktmerkmale: Recombinant Human Protein FAM19A4/FAM19A4 is produced with our E. coli expression system. The target protein is expressed with sequence (AA 35-140) of human TAFA4 fused with a His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

Andere Bezeichnung: Protein FAM19A4/FAM19A4 (FAM19A4 Produkte)

Synonyme: TAFA-4 Protein, TAFA4 Protein, C130034I18Rik Protein, Fam19a4 Tafa-4 Protein, Tafa-4 Protein, family with sequence similarity 19 member A4, C-C motif chemokine like Protein, family with sequence similarity 19, member A4 Protein, FAM19A4 Protein, Fam19a4 Protein

Hintergrund: FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.

Molekulargewicht: 14.1 kDa

UniProt: Q96LR4