RGMA Protein (AA 169-422) (His tag)

Produktnummer ABIN1945369

Produktdetails

Target: RGMA (RGM Domain Family, Member A (RGMA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 169-422

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RGMA Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Repulsive Guidance Molecule A/RGMA (N-6His)

Sequenz: MNHKVHHHHH HMPHLRTFTD RFQTCKVQGA WPLIDNNYLN VQVTNTPVLP GSAATATSKL TIIFKNFQEC VDQKVYQAEM DELPAAFVDG SKNGGDKHGA NSLKITEKVS GQHVEIQAKY IGTTIVVRQV GRYLTFAVRM PEEVVNAVED WDSQGLYLCL RGCPLNQQID FQAFHTNAEG TGARRLAAAS PAPTAPETFP YETAVAKCKE KLPVEDLYYQ ACVFDLLTTG DVNFTLAAYY ALEDVKMLHS NKDKLHLYER TRDLPG

Produktmerkmale: Recombinant Human Repulsive guidance molecule A/RGM domain family member A is produced with our E. coli expression system. The target protein is expressed with sequence(AA 169-422) of human RGMA fused with a His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: RGMA (RGM Domain Family, Member A (RGMA))

Andere Bezeichnung: Repulsive Guidance Molecule A/RGM Domain Family Member A (RGMA Produkte)

Synonyme: RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein

Hintergrund: Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

Molekulargewicht: 29.8 kDa

UniProt: Q96B86

Pathways: Tube Formation