IL18RAP Protein (AA 20-356) (Fc Tag,His tag)

Produktnummer ABIN1880644

Produktdetails

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-356

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses IL18RAP Protein ist gelabelt mit Fc Tag,His tag.

Verwendungszweck: Recombinant Human IL-18 Receptor Accessory Protein/IL-18RAcP/IL-1R7 (C-Fc-6His)

Sequenz: FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKRVDD IEGRMDEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Produktmerkmale: Recombinant Human IL-28A/B (IFN-lambda 2/3) is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe20-Arg356) of Human IFNL2 fused with a polyhistidine tag and FC tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Andere Bezeichnung: Interleukin-18 Receptor Accessory Protein/IL18RAP (IL18RAP Produkte)

Synonyme: IL18RAP Protein, ACPL Protein, CD218b Protein, CDw218b Protein, IL18RB Protein, interleukin 18 receptor accessory protein Protein, IL18RAP Protein, Il18rap Protein

Hintergrund: IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

Molekulargewicht: 66.4 kDa

UniProt: O95256