Recombinant Human Sentrin-specific protease 2/SENP2 is produced with our E. coli expression system. The target protein is expressed with sequence (Asp363-Leu589) of Human SENP2 fused with a 6His tag at the N-terminus.
Reinheit
> 95 % as determined by reducing SDS-PAGE.
Sterilität
0.2 μm filtered
Endotoxin-Niveau
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
SENP2
Spezies: Human
Wirt: Tobacco (Nicotiana tabacum)
Recombinant
>80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, SDS
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Supplied as a 0.2 μm filtered solution of 50 mM HEPES,5 % Glycerol, pH 7.4.
Handhabung
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung
-80 °C
Informationen zur Lagerung
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Haltbarkeit
6 months
Target
SENP2
(SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
2310007L05Rik Protein, 4930538C18Rik Protein, AI646780 Protein, AW554757 Protein, Smt3ip2 Protein, SuPr-1 Protein, mKIAA1331 Protein, AXAM2 Protein, SMT3IP2 Protein, Axam Protein, SUMO/sentrin specific peptidase 2 Protein, SUMO1/sentrin/SMT3 specific peptidase 2 Protein, Sumo1/sentrin/SMT3 specific peptidase 2 Protein, Senp2 Protein, SENP2 Protein
Sub Type
Fusionprotein
Hintergrund
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.