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SENP2 Protein (AA 363-589) (His tag,SUMO Tag)

SENP2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1880578
  • Target Alle SENP2 Proteine anzeigen
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 363-589
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses SENP2 Protein ist gelabelt mit His tag,SUMO Tag.
    Verwendungszweck
    Recombinant Human Sentrin-Specific Protease 2/SENP2 (N-6His, SUMO tag)
    Sequenz
    DDLLELTEDM EKEISNALGH GPQDEILSSA FKLRITRGDI QTLKNYHWLN DEVINFYMNL LVERNKKQGY PALHVFSTFF YPKLKSGGYQ AVKRWTKGVN LFEQEIILVP IHRKVHWSLV VIDLRKKCLK YLDSMGQKGH RICEILLQYL QDESKTKRNS DLNLLEWTHH SMKPHEIPQQ LNGSDCGMFT CKYADYISRD KPITFTQHQM PLFRKKMVWE ILHQQLL
    Produktmerkmale
    Recombinant Human Sentrin-specific protease 2/SENP2 is produced with our E. coli expression system. The target protein is expressed with sequence (Asp363-Leu589) of Human SENP2 fused with a 6His tag at the N-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SENP2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 50 mM HEPES,5 % Glycerol, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Andere Bezeichnung
    SENP2 (SENP2 Produkte)
    Synonyme
    2310007L05Rik Protein, 4930538C18Rik Protein, AI646780 Protein, AW554757 Protein, Smt3ip2 Protein, SuPr-1 Protein, mKIAA1331 Protein, AXAM2 Protein, SMT3IP2 Protein, Axam Protein, SUMO/sentrin specific peptidase 2 Protein, SUMO1/sentrin/SMT3 specific peptidase 2 Protein, Sumo1/sentrin/SMT3 specific peptidase 2 Protein, Senp2 Protein, SENP2 Protein
    Sub Type
    Fusionprotein
    Hintergrund
    SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
    Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.
    Molekulargewicht
    26.8 kDa
    UniProt
    Q9HC62
    Pathways
    Chromatin Binding
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