proBNP Protein
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- Target Alle proBNP Produkte
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Reinheit
- > 95 % by SDS-PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS (pH 7.5)
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C
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- Target
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Andere Bezeichnung
- Pro-BNP (proBNP Produkte)
- Synonyme
- BNP Protein, natriuretic peptide B Protein, NPPB Protein
- Hintergrund
- Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is released from the cardiac ventricles in response to increased wall tension. Rapid measurement of BNP is useful in establishing or excluding the diagnosis of congestive heart failure in patients with acute dyspnea. BNP is secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.
- Molekulargewicht
- 17 kDa
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