FKBP4 Protein (AA 1-459) (His tag)

Produktnummer ABIN1692481

Produktdetails

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-459

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FKBP4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP4/FKBP4 (C-6His)

Sequenz: MTAEEMKATE SGAQSAPLPM EGVDISPKQD EGVLKVIKRE GTGTEMPMIG DRVFVHYTGW LLDGTKFDSS LDRKDKFSFD LGKGEVIKAW DIAIATMKVG EVCHITCKPE YAYGSAGSPP KIPPNATLVF EVELFEFKGE DLTEEEDGGI IRRIQTRGEG YAKPNEGAIV EVALEGYYKD KLFDQRELRF EIGEGENLDL PYGLERAIQR MEKGEHSIVY LKPSYAFGSV GKEKFQIPPN AELKYELHLK SFEKAKESWE MNSEEKLEQS TIVKERGTVY FKEGKYKQAL LQYKKIVSWL EYESSFSNEE AQKAQALRLA SHLNLAMCHL KLQAFSAAIE SCNKALELDS NNEKGLFRRG EAHLAVNDFE LARADFQKVL QLYPNNKAAK TQLAVCQQRI RRQLAREKKL YANMFERLAE EENKAKAEAS SGDHPTDTEM KEEQKSNTAG SQSQVETEAL EHHHHHH

Produktmerkmale: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4/FKBP4 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala459) of Human FKBP4 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,10 % glycerol, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Andere Bezeichnung: FKBP4 (FKBP4 Produkte)

Synonyme: HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein

Sub Type: Fusionprotein

Hintergrund: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP4, 51kDa FK506-binding protein, 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4

Molekulargewicht: 52.8 kDa

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway