C1QBP Protein (AA 74-282) (His tag)

Produktnummer ABIN1692169

Produktdetails

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 74-282

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses C1QBP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human C1QBP/HABP1 (C-6His)

Sequenz: MLHTDGDKAF VDFLSDEIKE ERKIQKHKTL PKMSGGWELE LNGTEAKLVR KVAGEKITVT FNINNSIPPT FDGEEEPSQG QKVEEQEPEL TSTPNFVVEV IKNDDGKKAL VLDCHYPEDE VGQEDEAESD IFSIREVSFQ STGESEWKDT NYTLNTDSLD WALYDHLMDF LADRGVDNTF ADELVELSTA LEHQEYITFL EDLKSFVKSQ LEHHHHHH

Produktmerkmale:

Recombinant Human C1QBP/HABP1 (C-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris, 20 % Glycerol, 1 mM DTT, pH 7.5.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Andere Bezeichnung: Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial/C1QBP (C1QBP Produkte)

Synonyme: SF2 Protein, X38k Protein, gC1qR Protein, C1QBP Protein, GC1QBP Protein, HABP1 Protein, SF2p32 Protein, gC1Q-R Protein, p32 Protein, AA407365 Protein, AA986492 Protein, D11Wsu182e Protein, P32 Protein, gC1qBP Protein, Habp1 Protein, complement C1q binding protein Protein, complement component 1, q subcomponent binding protein S homeolog Protein, complement component 1, q subcomponent binding protein Protein, C1QBP Protein, c1qbp.S Protein, LOC100227158 Protein, C1qbp Protein

Hintergrund: Recombinant Human Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial/C1QBP is produced with our E. coli expression system. The target protein is expressed with sequence (Leu74-Gln282) of Human C1QBP fused with a 6His tag at the C-terminus.
Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.

Molekulargewicht: 24.9 kDa

UniProt: Q07021

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly