Fission 1 Protein (FIS1) (AA 1-122) (His tag)
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- Target Alle Fission 1 (FIS1) Proteine anzeigen
- Fission 1 (FIS1)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-122
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Fission 1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Mitochondrial Fission 1 Protein/FIS1 (C-6His)
- Sequenz
- MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DGVEHHHHHH
- Produktmerkmale
- Recombinant Human Mitochondrial Fission 1 Protein/FIS1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly122) of Human FIS1 fused with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FIS1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
- Handhabung
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Lagerung
- 4 °C/-20 °C/-80 °C
- Informationen zur Lagerung
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Haltbarkeit
- 3 months
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- Target
- Fission 1 (FIS1)
- Andere Bezeichnung
- FIS1 (FIS1 Produkte)
- Synonyme
- TTC11 Protein, 2010003O14Rik Protein, Ttc11 Protein, fission, mitochondrial 1 Protein, FIS1 Protein, Fis1 Protein
- Sub Type
- Fusionprotein
- Hintergrund
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Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
Alternative Names: Mitochondrial Fission 1 Protein, FIS1 Homolog, hFis1, Tetratricopeptide Repeat Protein 11, TPR Repeat Protein 11, FIS1, TTC11, CGI-135 - Molekulargewicht
- 15.2 kDa
- UniProt
- Q9Y3D6
- Pathways
- Positive Regulation of Endopeptidase Activity
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