Parvin alpha Protein (AA 1-372) (His tag)

Produktnummer ABIN1691893

Produktdetails

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-372

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Parvin alpha Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human α-Parvin/PARVA/MXRA2 (C-6His)

Sequenz: MATSPQKSPS APKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV GERIIVKDLA EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV LEKINETLKL PPRSIKWNVD SVHAKSLVAI LHLLVALSQY FRAPIRLPDH VSIQVVVVQK REGILQSRQI QEEITGNTEA LSGRHERDAF DTLFDHAPDK LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM GLLEGYFVPL HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV LYNLFTKYRN VELEHHHHHH

Produktmerkmale: Recombinant Human Alpha-Parvin/PARVA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Glu372) of Human PARVA fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 40 % Glycerol, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Andere Bezeichnung: PARVA (PARVA Produkte)

Synonyme: CH-ILKBP Protein, MXRA2 Protein, Actp Protein, 2010012A22Rik Protein, 5430400F08Rik Protein, AI225929 Protein, AU042898 Protein, Parvin Protein, parva Protein, wu:fc59e06 Protein, zgc:101643 Protein, PARVA Protein, Parva Protein, parvin alpha Protein, parvin, alpha Protein, parvin, alpha a Protein, PARVA Protein, Parva Protein, parvaa Protein

Sub Type: Fusionprotein

Hintergrund: Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
Alternative Names: Alpha-Parvin, Actopaxin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, Matrix-Remodeling-Associated Protein 2, PARVA, MXRA2

Molekulargewicht: 43.2 kDa

UniProt: Q9NVD7

Pathways: Smooth Muscle Cell Migration