ANG Protein (AA 26-147) (His tag)

Produktnummer ABIN1046529

Produktdetails

Target: ANG (Angiogenin (ANG))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-147

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ANG Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS), ELISA

Sequenz: DNSRYTHFLT QHYDAKPQGR DDRYCESIMR RRGLTSPCKD INTFIHGNKR SIKAICENKN GNPHRENLRI SKSSFQVTTC KLHGGSPWPP CQYRATAGFR NVVVACENGL PVHLDQSIFR RP-

Produktmerkmale: May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Referenzen

Zhang, Rosenberg: "Diversifying selection of the tumor-growth promoter angiogenin in primate evolution." in: Molecular biology and evolution, Vol. 19, Issue 4, pp. 438-45, (2002) (PubMed).

Kurachi, Davie, Strydom, Riordan, Vallee: "Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor." in: Biochemistry, Vol. 24, Issue 20, pp. 5494-9, (1986) (PubMed).

Antigendetails

Target: ANG (Angiogenin (ANG))

Andere Bezeichnung: Angiogenin (ANG Produkte)

Synonyme: ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, ANG Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, ANG1 Protein, angiogenin Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ribonuclease A family member k6 Protein, ANG Protein, Ang Protein, RNASE6 Protein

Hintergrund: Synonyms: Ribonuclease 5,Nase 5

Molekulargewicht: 18 kDa