SYNCRIP Protein (AA 2-191, partial) (GST tag)

Produktnummer ABIN7479304

Produktdetails

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-191, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SYNCRIP Protein ist gelabelt mit GST tag.

Applikation: ELISA

Sequenz: ATEHVNGNGT EEPMDTTSAV IHSENFQTLL DAGLPQKVAE KLDEIYVAGL VAHSDLDERA IEALKEFNED GALAVLQQFK DSDLSHVQNK SAFLCGVMKT YRQREKQGTK VADSSKGPDE AKIKALLERT GYTLDVTTGQ RKYGGPPPDS VYSGQQPSVG TEIFVGKIPR DLFEDELVPL FEKAGPIWDL

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 95 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Antigendetails

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Andere Bezeichnung: Heterogeneous nuclear ribonucleoprotein Q protein (SYNCRIP Produkte)

Synonyme: GRY-RBP Protein, GRYRBP Protein, HNRNPQ Protein, HNRPQ1 Protein, NSAP1 Protein, PP68 Protein, hnRNP-Q Protein, 2610109K23Rik Protein, 4632417O19Rik Protein, Nsap1 Protein, Nsap1l Protein, pp68 Protein, nsap1 Protein, wu:fe02c03 Protein, wu:fe47h09 Protein, SYNCRIP Protein, hnrpq1 Protein, gry-rbp Protein, rp1-3j17.2 Protein, synaptotagmin binding cytoplasmic RNA interacting protein Protein, synaptotagmin binding, cytoplasmic RNA interacting protein Protein, synaptotagmin binding cytoplasmic RNA interacting protein S homeolog Protein, SYNCRIP Protein, Syncrip Protein, syncrip Protein, syncrip.S Protein

Hintergrund: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.

Molekulargewicht: 48.2 kD

UniProt: O60506