Dynamin 1-Like Protein (DNM1L) (AA 1-710) (GST tag)

Produktnummer ABIN1351855

Produktdetails

Target: Dynamin 1-Like (DNM1L)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-710

Spezies: Human

Quelle: Wheat germ

Aufreinigungstag / Konjugat: Dieses Dynamin 1-Like Protein ist gelabelt mit GST tag.

Applikation: ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)

Verwendungszweck: DNM1L (Human) Recombinant Protein (P01)

Sequenz: MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

Produktmerkmale: Human DNM1L full-length ORF ( AAH24590.1, 1 a.a. - 710 a.a.) recombinant protein with GST-tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Referenzen

Qi, Qvit, Su, Mochly-Rosen: "A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity." in: Journal of cell science, Vol. 126, Issue Pt 3, pp. 789-802, (2013) (PubMed).

Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).

Guo, Disatnik, Monbureau, Shamloo, Mochly-Rosen, Qi: "Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration." in: The Journal of clinical investigation, Vol. 123, Issue 12, pp. 5371-88, (2013) (PubMed).

Qi, Disatnik, Shen, Sobel, Mochly-Rosen: "Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo." in: Molecular biology of the cell, Vol. 22, Issue 2, pp. 256-65, (2011) (PubMed).

Antigendetails

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L (DNM1L Produkte)

Synonyme: DLP1 Protein, DRP1 Protein, DVLP Protein, DYMPLE Protein, EMPF Protein, HDYNIV Protein, 6330417M19Rik Protein, AI450666 Protein, Dlp1 Protein, Dnmlp1 Protein, Drp1 Protein, python Protein, Dnml1 Protein, dnm1l Protein, MGC53850 Protein, zgc:66163 Protein, DNM1L Protein, 18.m06247 Protein, CG3210 Protein, DRP Protein, Dmel\CG3210 Protein, Dnm1/Drp1 Protein, Drp Protein, Drp-1 Protein, drp-1 Protein, drp1 Protein, frat Protein, l(2)22Fc Protein, l(2)22Fd Protein, l(2)ND2 Protein, l(2)ND3 Protein, dynamin 1 like Protein, dynamin 1-like Protein, dynamin 1-like L homeolog Protein, dynamin-1-like Protein, dynamin-1-like protein Protein, dynamin-like protein Protein, Dynamin related protein 1 Protein, DNM1L Protein, Dnm1l Protein, dnm1l.L Protein, dnm1l Protein, LOC100369408 Protein, LOC411472 Protein, dyn1 Protein, cgd1_580 Protein, EHI_052740 Protein, PVX_092875 Protein, BBOV_II002980 Protein, Drp1 Protein

Hintergrund: Full Gene Name: dynamin 1-like
Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1

Gen-ID: 10059