RBP4 Protein (AA 19-201) (DYKDDDDK Tag)

Produktnummer ABIN1344327

Produktdetails

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-201

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RBP4 Protein ist gelabelt mit DYKDDDDK Tag.

Applikation: SDS-PAGE (SDS)

Kreuzreaktivität: Ratte (Rattus)

Produktmerkmale: Rat RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag.

Reinheit: >90 % (SDS-PAGE)

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.2.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Haltbarkeit: 3 months

Referenzen

Casillas-Ramírez, Alfany-Fernández, Massip-Salcedo, Juan, Planas, Serafín, Pallàs, Rimola, Rodés, Peralta: "Retinol-binding protein 4 and peroxisome proliferator-activated receptor-? in steatotic liver transplantation." in: The Journal of pharmacology and experimental therapeutics, Vol. 338, Issue 1, pp. 143-53, (2011) (PubMed).

Antigendetails

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Andere Bezeichnung: RBP4 (RBP4 Produkte)

Synonyme: RDCCAS Protein, RBP Protein, RNBP Protein, rbp4 Protein, MGC54038 Protein, srbp Protein, PRBP Protein, RBPA Protein, Rbp-4 Protein, fb23c12 Protein, rbp Protein, wu:fb23c12 Protein, wu:fb58d04 Protein, wu:fb72b04 Protein, zgc:86911 Protein, retinol binding protein 4 Protein, renin binding protein Protein, retinol binding protein 4 S homeolog Protein, retinol binding protein 4 A, plasma Protein, retinol binding protein 4, plasma Protein, retinol binding protein 4 L homeolog Protein, RBP4 Protein, RENBP Protein, rbp4.S Protein, rbp4 Protein, Rbp4 Protein, RBP4A Protein, rbp4.L Protein

Hintergrund: Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Molekulargewicht: ~23kDa (SDS-PAGE)

UniProt: P04916

Pathways: Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response