IGF-like family receptor 1 (IGFLR1) (AA 23-154) protein (Fc Tag)
IGFLR1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
SDS
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- Target Alle IGF-like family receptor 1 (IGFLR1) Proteine anzeigen
- IGF-like family receptor 1 (IGFLR1)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 23-154
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Fc Tag
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to its ligand IGFL3 (human) in the subnanomolar range (< 1 ng /mL).
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.05EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IGFLR1 Protein
-
IGF-like family receptor 1 (IGFLR1) (AA 23-163) protein (His tag)
IGFLR1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- IGF-like family receptor 1 (IGFLR1)
- Andere Bezeichnung
- IGFLR1 (IGFLR1 Produkte)
- Hintergrund
- Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
- Molekulargewicht
- ~50kDa (SDS-PAGE)
- UniProt
- Q9H665
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