PEDF Protein (AA 20-418) (DYKDDDDK Tag)

Produktnummer ABIN1344132

Produktdetails

Target: PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-418

Spezies: Human

Quelle: CHO Cells

Aufreinigungstag / Konjugat: Dieses PEDF Protein ist gelabelt mit DYKDDDDK Tag.

Applikation: SDS-PAGE (SDS)

Kreuzreaktivität: Human

Produktmerkmale: Human PEDF (aa 20-418) is fused at the C-terminus of to a FLAG®-tag.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with 100 μL sterile distilled water.

Konzentration: Lot specific

Buffer: Lyophilized. Contains PBS.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))

Andere Bezeichnung: PEDF (SERPINF1 Produkte)

Synonyme: EPC-1 Protein, OI12 Protein, OI6 Protein, PEDF Protein, MGC82984 Protein, SERPINF1 Protein, AI195227 Protein, Pedf Protein, Pedfl Protein, Sdf3 Protein, Dmrs91 Protein, zgc:92072 Protein, serpin family F member 1 Protein, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 Protein, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog Protein, serine (or cysteine) peptidase inhibitor, clade F, member 1 Protein, SERPINF1 Protein, serpinf1 Protein, serpinf1.L Protein, Serpinf1 Protein

Hintergrund: Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and foetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Molekulargewicht: ~47kDa (SDS-PAGE)

UniProt: P36955