FNDC5 Protein (AA 29-140)
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- Target Alle FNDC5 Proteine anzeigen
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 29-140
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Spezies
- Human, Maus
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Irisin (human, aa 32-143 / mouse, aa 29-140) is untagged. Irisin has 100 % identity between mouse, rat, monkey and human.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC5 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 100 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- Andere Bezeichnung
- Irisin (FNDC5 Produkte)
- Synonyme
- FRCP2 Protein, irisin Protein, 1500001L03Rik Protein, AI836596 Protein, C87088 Protein, PeP Protein, Pxp Protein, fndc5 Protein, si:dkey-264p5.1 Protein, zgc:158684 Protein, fibronectin type III domain containing 5 Protein, fibronectin type III domain containing 5b Protein, FNDC5 Protein, Fndc5 Protein, fndc5b Protein
- Hintergrund
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
- Molekulargewicht
- ~12kDa
- UniProt
- Q8NAU1
- Pathways
- Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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