TDP1 Protein (His tag)
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- Target Alle TDP1 Proteine anzeigen
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses TDP1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TDP1 Protein
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- Kommentare
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Synonyms: Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Andere Bezeichnung
- TDP1 (TDP1 Produkte)
- Synonyme
- 2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
- Hintergrund
- Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 35.8 kDa (318aa)
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