DEDD Protein (His tag)
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- Target Alle DEDD Proteine anzeigen
- DEDD (Death Effector Domain Containing (DEDD))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses DEDD Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DEDD Protein
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- Kommentare
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Synonyms: Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- DEDD (Death Effector Domain Containing (DEDD))
- Andere Bezeichnung
- DEDD (DEDD Produkte)
- Synonyme
- CASP8IP1 Protein, DEDD1 Protein, DEFT Protein, FLDED1 Protein, Dedpro1 Protein, KE05 Protein, Deft Protein, death effector domain containing Protein, death effector domain-containing Protein, DEDD Protein, Dedd Protein
- Hintergrund
- Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 38.9 kDa (338aa)
- NCBI Accession
- NP_127491
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