UBE2M Protein (His tag)

Produktnummer ABIN1098637

Produktdetails

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2M Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by using conventional chromatography.

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: NEDD8-conjugating enzyme Ubc12, hUbc12, UBC-RS2, UBC12

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.2 M NaCl, 1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Andere Bezeichnung: UBE2M (ube2m Produkte)

Synonyme: DDBDRAFT_0204633 Protein, DDBDRAFT_0238042 Protein, DDB_0204633 Protein, DDB_0238042 Protein, UBC-RS2 Protein, UBC12 Protein, hUbc12 Protein, 2510040H03Rik Protein, Ubc-rs2 Protein, ubiquitin conjugating enzyme E2M Protein, ubiquitin-conjugating enzyme E2M Protein, ubiquitin conjugating enzyme E2 M Protein, NEDD8-conjugating enzyme Protein, ubiquitin conjugating enzyme E2M S homeolog Protein, ube2m Protein, LOC692934 Protein, UBE2M Protein, Ube2m Protein, ube2m.S Protein

Hintergrund: UBE2M, also known as NEDD8-conjugating enzyme Ubc12, belongs to the ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. Recombinant human UBE2M protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Molekulargewicht: 23.5 kDa (207aa) confirmed by MALDI-TOF

NCBI Accession: NP_003960