Glucose-6-Phosphate Dehydrogenase (G6PD) protein (His tag)

Details zu Produkt Nr. ABIN1098613, Anbieter: Anmelden zum Anzeigen
Proteinname
  • G6PD1
  • g6pd
  • G6pd
  • G6pdx
  • g6pdh
  • g6pd2
  • fj78b06
  • wu:fj78b06
  • si:dkey-90a13.8
  • BA3433
  • G28A
  • G6PD
  • Gpdx
  • glucose-6-phosphate dehydrogenase
  • glucose-6-phosphate 1-dehydrogenase
  • glucose-6-phosphate 1-dehydrogenase (G6PD)
  • glucose-6-P dehydrogenase
  • glucose-6-phosphate dehydrogenase L homeolog
  • glucose-6-phosphate 1-dehydrogenase Zwf
  • glucose-6-phosphate dehydrogenase X-linked
  • G6PD
  • g6pd
  • g6pD
  • zwf
  • LOC100120232
  • LACBIDRAFT_188936
  • G6pd
  • g6pd.L
  • CNG03280
  • Tb10.70.5200
  • G6pdx
Spezies
Human
15
5
3
3
2
2
1
1
1
Quelle
Hi-5 Cells
10
5
3
3
3
2
2
1
1
1
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses Glucose-6-Phosphate Dehydrogenase Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Reinigung purified by using conventional chromatography.
Reinheit > 95 % by SDS - PAGE
Proteinname
Hintergrund Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia. Recombinant human G6PD protein, fused to His-tag at N-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
Molekulargewicht 61.4kDa (535aa)
NCBI Accession NP_001035810
Pathways Regulation of Systemic Arterial Blood Pressure by Hormones
Kommentare

Synonyms: glucose-6-phosphate 1-dehydrogenase, G6PD1

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/ml (determined by Bradford assay)
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 MM PMSF, 2 mM EDTA, 2 mM DTT, 200 mM NaCl
Lagerung 4 °C
Informationen zur Lagerung Avoid repeated freezing and thawing cycles.
Bilder des Herstellers
 image for Glucose-6-Phosphate Dehydrogenase (G6PD) protein (His tag) (ABIN1098613) Glucose-6-Phosphate Dehydrogenase (G6PD) protein (His tag)
Allgemeine Veröffentlichungen Huang, Choi, Au, Au, Lam, Engel et al.: "Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PD(Plymouth) and G6PD(Mahidol): Evidence for defective protein folding as the basis of ..." in: Molecular genetics and metabolism, Vol. 93, Issue 1, pp. 44-53, 2007 (PubMed).

Kuliszkiewicz-Janus, Zimny: "[Glucose-6-phosphate dehydrogenase (G6PD) deficiency--a cause of anaemia in pregnant women]." in: Polskie Archiwum Medycyny Wewn?trznej, Vol. 110, Issue 5, pp. 1327-33, 2006 (PubMed).

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