TDP2 Protein (His tag)

Produktnummer ABIN7280202

Produktdetails

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TDP2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Tyrosyl-DNA phosphodiesterase 2, AD022, dJ30M3.3, EAP2, EAPII, RP1-30M3.3, TTRAP

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Andere Bezeichnung: TDP2 (TDP2 Produkte)

Synonyme: AD022 Protein, EAP2 Protein, EAPII Protein, TTRAP Protein, dJ30M3.3 Protein, hTDP2 Protein, ad022 Protein, eap2 Protein, ttrap Protein, D13Ertd656e Protein, Ttrap Protein, tdp2 Protein, ttrapl Protein, tyrosyl-DNA phosphodiesterase 2 Protein, tyrosyl-DNA phosphodiesterase 2 S homeolog Protein, tyrosyl-DNA phosphodiesterase 2b Protein, TDP2 Protein, tdp2.S Protein, Tdp2 Protein, tdp2b Protein

Hintergrund: TDP2 is a member of a superfamily of divalent cation-dependent phosphodiesterases. The protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. Recombinant human TDP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 43.3 kDa (385aa) confirmed by MALDI-TOF

NCBI Accession: NP_057698